COLUMBIA, South Carolina, December 2 /PRNewswire/ --

- Semantic Search and Knowledge Discovery Software Company Recognized for
Innovation in Eighth Annual EC100 List

Collexis Holdings, Inc. (OTC Bulletin Board: CLXS), a leading developer
of semantic search and knowledge discovery software, announced today that it
has been named by EContent magazine as one of the 100 Companies that Matter
Most in the Digital Content Industry. The list, compiled annually by
EContent, recognizes companies in a variety of categories in the digital
content industry and reinforces the importance of digital content as a
resource that should be maximized by organizations.

"We are proud to be recognized as part of the EContent 100," said Bill
Kirkland, chief executive officer of Collexis. "It's truly an honor to be
included among industry forerunners like Apple, IBM and Microsoft and our
dedicated team strives to constantly innovate and excel in this dynamic
field."

EC100, now in its eighth year, is an annually updated list that
recognizes the continued expertise or renewed strength of some of the
industry's leaders, as well as innovation of newcomers to the field. Selected
by fourteen judges with experience ranging from publishing and content
management to online network analysis, Collexis joins the ranks of other
global content providers including Thomson Reuters, Reed Elsevier and many
others.

"We are proud of this list and of the companies on it," said Michelle
Manafy, EContent editor-in-chief. "Members of the EContent 100 List are the
companies empowering the content that fuels business today and we hope that
our readers find the list as valuable as we did the process of creating it."

About EContent

EContent is dedicated to one of the most essential commodities any
business has to offer -- content. While the digital era has provided
businesses with unprecedented access to content, it has also created an
exponentially increasing need to manage, store, and deliver that content in
ways that are efficient, effective, and affordable. And with this steady rise
in digital content challenges, EContent magazine is there to help guide
professionals with sound advice and breaking news. EContent is the most
respected source for information about the digital content industry. The
magazine has a mission to clearly identify and explain emerging digital
content trends, strategies, and resources that will help readers navigate the
content maze and find a clear path to profits and improved business
processes.

EContent delivers essential research, reporting, news, and analysis of
content related issues. It is essential reading for executives and
professionals involved in content creation, management, acquisition,
organization, and distribution in both commercial and enterprise
environments. EContent is the premier publication for the digital content
industry. (www.econtentmag.com)

About Collexis Holdings, Inc.

Collexis Holdings, Inc., a leading developer of semantic search and
knowledge discovery software is headquartered in Columbia, South Carolina
(USA) with major operations in Cincinnati, Ohio, Geldermalsen, the
Netherlands and Cologne, Germany. Collexis now offers the world's first
pre-populated scientific social network for life science researchers,
www.biomedexperts.com. Collexis' proprietary technology builds conceptual
profiles of text, called "Fingerprints", from documents, Websites, emails and
other digitized content and matches them with a comprehensive list of
pre-defined "Fingerprinted" concepts to make research results more relevant
and efficient. This matching of concepts eliminates the ambiguity and lack of
priority associated with word searches. The results are often described as
"finding needles in many haystacks." Through this novel approach, Collexis
can build unique applications to search, index and aggregate information as
well as prioritize, trend and predict data based on sources in multiple
industries without the limitations of language or dialect. Collexis' current
clients in the public, private and academic sectors include the Mayo Clinic;
Johns Hopkins University; Dana-Farber Cancer Institute, the University of
California, San Francisco; the University of South Carolina; Erasmus
University Library; Bristol-Myers Squibb; Lockheed Martin; the World Health
Organization; Wellcome Trust; the National Institutes of Health; and the U.S.
Department of Defense. Shares of Collexis common stock are traded under the
symbol CLXS on the OTC Bulletin Board (OTC BB). For more information, visit
www.collexis.com.

Forward-Looking Statements

Some of the statements made in this press release may constitute
forward-looking statements within the meaning of the Private Securities
Litigation Reform Act of 1995. These forward-looking statements are based on
management's current expectations and include known and unknown risks,
uncertainties and other factors, many of which the company is unable to
predict or control, that may cause the company's actual results or
performance to differ materially from any future results or performance
expressed or implied by such forward-looking statements. These risks and
uncertainties are in addition to other factors detailed from time to time in
the company's filings with the SEC, including the section entitled "Risk
Factors" in its transition report on Form 10-KSB for the period ended June
30, 2008. The company cautions investors that any forward-looking statements
made by the company are not necessarily indicative of future performance. The
company is not responsible for updating the information contained in this
press release beyond the published date, or for changes made to this document
by wire services or Internet services.